Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
B. Daley, H. M. Vieira, C. Rao…·R. L. Kortum
This study shows that targeting SOS1 or KSR1 enhances MEK inhibitor efficacy and prevents resistance in KRAS-mutated cancers, depending on specific KRAS and co-mutation status.
D. E. Frodyma, T. C. Troia, J. A. Berg…·K. W. Fisher
This study identifies PCK2 as a target of PGC-1β and ERRα that promotes glutamine metabolism and colorectal cancer survival through transcriptional regulation.
C. Rao, R. A. Svoboda, S. Southekal…·R. E. Lewis
The paper shows that KSR1-dependent signaling in CRC cells promotes SRSF9-mediated splicing of EPSTI1 mRNA, which drives EMT and metastasis.
D. H. Huisman, D. Chatterjee, R. A. Svoboda…·R. E. Lewis
This study shows KSR2 promotes self-renewal and clonogenicity in ASCL1-subtype SCLC by enhancing ERK signaling and tumor initiating capacity.
C. Rao, D. E. Frodyma, S. Southekal…·R. E. Lewis
This study shows KSR1 and ERK promote EMT by selectively translating EPSTI1, which facilitates the E-to N-cadherin switch and enhances migration and invasion in CRC cells.