Author

R. Ashfield

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

A. V. Hill· 2 shared P. Dulal· 2 shared S. J. Draper· 2 shared A. A. Walters· 1 shared A. Banyard· 1 shared A. D. Douglas· 1 shared A. Diouf· 1 shared A. Douglas· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. V. Hill

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Author profile →

3 papers

Recent·Most cited

Preclinical Development of a Stabilized RH5 Virus-Like Particle Vaccine that Induces Improved Anti-Malarial Antibodies

L. D. W. King, D. Pulido, J. R. Barrett, H. Davies, D. Quinkert, A. M. Lias, S. E. Silk, D. J. Pattinson, A. Diouf, B. G. Williams, K. McHugh, A. Rodrigues, C. A. Rigby, V. Strazza, J. Suurbaar, , S. J. Draper

This paper develops a stabilized RH5 VLP vaccine that induces improved anti-malarial antibodies compared to a soluble protein vaccine in preclinical studies.

bioRxiv · Jan 4, 2024Immunology

Characterisation of factors contributing to the performance of nonwoven fibrous matrices as substrates for adenovirus vectored vaccine stabilisation

P. Dulal, A. A. Walters, N. Hawkins, T. D. Claridge, K. Kowal, S. Neill, S. J. Russell, A. J. Ritchie, R. Ashfield, A. V. Hill, A. D. Douglas

The paper investigates fibrous matrices for adenovirus vaccine stabilisation, identifies polyvinyl alcohol as a key stabilising component, and develops a custom matrix for clinical translation.

bioRxiv · Jan 31, 2020Pharmacology & Toxicology

A simian-adenovirus-vectored rabies vaccine suitable for thermostabilisation and clinical development for low-cost single-dose pre-exposure prophylaxis

C. Wang, P. Dulal, X. Zhou, Z. Xiang, H. Goharriz, A. Banyard, N. Green, L. Brunner, R. Ventura, N. Collin, S. J. Draper, A. V. Hill, R. Ashfield, A. R. Fooks, H. C. Ertl, A. Douglas

This paper develops a simian-adenovirus-vectored rabies vaccine that can be thermostabilized and administered as a single dose, showing potent immunogenicity and potential for low-cost pre-exposure prophylaxis.

bioRxiv · Sep 4, 2018Immunology