K. J. Svensson

A PTER-dependent pathway of taurine metabolism linked to energy balance

This study identifies PTER as the taurine N-acetyltransferase/hydrolase, showing its role in regulating N-acetyltaurine levels and linking it to energy balance and metabolic phenotypes.

Mitochondrial uncoupler and retinoic acid synergistically induce differentiation and inhibit proliferation in neuroblastoma

A class of secreted mammalian peptides with potential to expand cell-cell communication

The paper identifies a new class of secreted mammalian peptides, capped peptides, which may regulate cell-cell communication through post-translational modifications.

AlphaFold2 enables accurate deorphanization of ligands to single-pass receptors

The paper uses AlphaFold2 to predict ligand-receptor interactions for single-pass transmembrane receptors with high accuracy.

Single-cell analysis of non-alcoholic fatty livers identifies a role for the constitutive androstane receptor

The paper uses single-cell RNA sequencing to identify lipid synthesis clusters and links the constitutive androstane receptor to hepatic steatosis in NAFLD.

G protein-coupled receptor 151 regulates glucose metabolism and hepatic gluconeogenesis

This study identifies GPR151 as a regulator of hepatic gluconeogenesis and links its dysfunction to type 2 diabetes risk.

Phosphoproteomic mapping reveals distinct signaling actions and activation of protein synthesis and muscle hypertrophy by Isthmin-1

This study identifies distinct phosphoproteomic effects of Ism1 compared to insulin, revealing novel pathways in muscle hypertrophy and protein synthesis.