Author

H. D. Kim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:DNA methylation· 3 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

D. W. B. Broadwater· 2 shared J. Jeong· 2 shared A. W. Cook· 1 shared D. R. Hart· 1 shared H.-Y. Lee· 1 shared J. Gumbart· 1 shared J. Kim· 1 shared J. Shin· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBiophysics

D. W. B. Broadwater

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Weak tension accelerates hybridization and dehybridization of short oligonucleotides

D. R. Hart, J. Jeong, J. Gumbart, H. D. Kim

This study measures how weak tension affects DNA hybridization and dehybridization rates using a DNA bow assay and single-molecule FRET, finding increased rates with tension for various sequences.

bioRxiv · Apr 19, 2022Biophysics

Inhibition of Ras1-MAPK pathways for hypha formation by novel drug candidates in Candida albicans

Y. K. Park, J. Shin, H.-Y. Lee, H. D. Kim, J. Kim

This paper identifies small carbazole derivatives that inhibit C. albicans morphogenesis and pathogenicity by targeting the Ras1/MAPK pathway, showing efficacy in drug-resistant strains and in vivo.

bioRxiv · Jul 6, 2021 · PreprintMicrobiology

First passage time study of DNA strand displacement

D. W. B. Broadwater, A. W. Cook, H. D. Kim

This study uses smFRET to analyze the kinetics of DNA strand displacement, finding sequence-dependent variations in displacement times and a single-step displacement time range of 30-300 microseconds.

Biophysical Journal · Jun 1, 2021Peer-reviewedBiophysics

Determinants of cyclization-decyclization kinetics of short DNA with sticky ends

J. Jeong, H. D. Kim

The paper measures cyclization and decyclization rates of short DNA with sticky ends using single-molecule FRET, finding length-dependent oscillations in decyclization rates and agreement with a three-state cyclization model.

bioRxiv · Dec 21, 2018Biophysics

ERASE: a novel surface reconditioning strategy for single-molecule experiments

D. W. B. Broadwater, R. B. Altman, S. C. Blanchard, H. D. Kim

The paper introduces ERASE, a method to reuse single-molecule experiment surfaces by removing biomolecules via DNA strand displacement, enabling repeated use and parallel molecule analysis.

bioRxiv · Mar 15, 2018Biophysics