Dual functioning by the PhoR sensor is a key determinant to Mycobacterium tuberculosis virulence
P. R. Singh, H. Goar, P. Paul, K. Mehta, B. Bamniya, V. Anil Kumar, R. Bansal, H. Khan, S. Karthikeyan, D. SARKAR
This study identifies PhoR as a dual-function sensor kinase/phosphatase in M. tuberculosis, revealing its role in virulence through pH and salt sensing and regulation of the PhoP regulon.
bioRxiv · Apr 13, 2023 · PreprintMicrobiology