Author

R. Barnes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

A. E. Carpenter· 1 shared A. Filby· 1 shared A. M. Lynch· 1 shared B. J. Rees· 1 shared C. A. Thornton· 1 shared C. Chen· 1 shared C. M. Barnes· 1 shared C. Mahn· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. E. Carpenter

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Author profile →

4 papers

Recent·Most cited

A mathematical model for velocity-selective arterial spin labeling

T. Liu, E. C. Wong, D. Bolar, C. Chen, R. Barnes

The paper develops a mathematical model for velocity-selective arterial spin labeling (VSASL) to analyze key concepts and predict performance characteristics.

bioRxiv · Aug 28, 2023Bioengineering

Macrophage-targeted lipid nanoparticle delivery of microRNA-146a to mitigate hemorrhagic shock-induced acute respiratory distress syndrome

Q. Fei, E. M. Shalosky, R. Barnes, V. C. Shukla, M. N. Ballinger, L. Farkas, R. J. Lee, S. N. Ghadiali, J. A. Englert

This study develops mannosylated lipid nanoparticles to deliver miR-146a to alveolar macrophages, reducing lung inflammation with lower doses in a mouse model of hemorrhagic shock-induced acute respiratory distress syndrome.

bioRxiv · Feb 17, 2023Pharmacology & Toxicology

Inter-laboratory automation of the in vitro micronucleus assay using imaging flow cytometry and deep learning

J. W. Wills, J. R. Verma, B. J. Rees, D. S. G. Harte, Q. Haxhiraj, C. M. Barnes, R. Barnes, M. A. Rodrigues, M. Doan, A. Filby, R. E. Hewitt, C. A. Thornton, J. G. Cronin, J. D. Kenny, R. Buckley, , P. Rees

This paper automates the in vitro micronucleus assay using imaging flow cytometry and deep learning, achieving high classification accuracy across laboratories.

bioRxiv · May 5, 2021Pharmacology & Toxicology

TIN2 facilitates TRF1-mediated trans- and cis-interactions on physiologically relevant long telomeric DNA

H. Pan, P. Kaur, M. Liu, P. Xu, C. Mahn, R. Barnes, Q. Tang, P. Hao, D. Bhattaram, C. You, J. Piehler, K. Weninger, R. Riehn, S. Smith, P. L. Opersko, H. Wang

This study shows TIN2 promotes TRF1-mediated DNA-DNA bridging on telomeres, stabilizing interactions that depend on telomere length and sequence.

bioRxiv · Sep 12, 2020 · PreprintBiophysics