Author

R. Barreira da Silva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

I. Mellman· 2 shared M. Albert· 2 shared A. Baz Morelli· 1 shared A. de Maziere· 1 shared A. Verkman· 1 shared C. Chalouni· 1 shared C. Eidenschenk· 1 shared C. Everett· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

I. Mellman

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2 papers

Recent·Most cited

ImmunologyNature ImmunologyPeer-reviewedMar 21, 2022

Loss of the intracellular enzyme QPCTL limits chemokine function and reshapes myeloid infiltration to augment tumor immunity

R. Barreira da Silva, R. Leitao, X. Pechuan…·M. Albert

This study shows that QPCTL inhibition reduces monocyte migration and alters myeloid cell infiltration, enhancing anti-tumor immunity when combined with anti-PD-L1 therapy.

DOI 10.1038/s41590-022-01153-x

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivAug 19, 2020

Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation

S. Nalle, R. Barreira da Silva, H. Zhang…·I. Mellman

This study identifies aquaporin-3 as a regulator of endosome-to-cytosol transfer by facilitating hydrogen peroxide entry, which induces lipid peroxidation and antigen release.

DOI 10.1371/journal.pone.0238484

mouseexperimental assay

𝕏 PostBluesky