Author

A. de Maziere

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

J. Klumperman· 2 shared A. Ashkenazi· 1 shared A. Baz Morelli· 1 shared A. Verkman· 1 shared C. Chalouni· 1 shared G. J. Jensen· 1 shared G. Posthuma· 1 shared H. Zhang· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

J. Klumperman

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2 papers

Recent·Most cited

The stress-sensing domain of activated IRE1α forms helical filaments in narrow ER membrane tubes

S. D. Carter, N.-H. Tran, A. De Maziere, A. Ashkenazi, J. Klumperman, G. J. Jensen, P. Walter

This study determines the in-situ structure of IRE1 oligomers in ER tubes using cryo-CLEM, revealing helical filaments formed by IRE1 lumenal domain dimers and suggesting positive feedback in IRE1 signaling.

bioRxiv · Feb 24, 2021Cell Biology

Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation

S. Nalle, R. Barreira da Silva, H. Zhang, M. Decker, C. Chalouni, M. Xu, G. Posthuma, A. de Maziere, J. Klumperman, A. Baz Morelli, S. Fleire, A. Verkman, S. Trombetta, M. Albert, I. Mellman

This study identifies aquaporin-3 as a regulator of endosome-to-cytosol transfer by facilitating hydrogen peroxide entry, which induces lipid peroxidation and antigen release.

bioRxiv · Aug 19, 2020Immunology