MicrobiologybioRxiv
Genetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway
R. C. S. Edgar, G. Siddiqui, K. Hjerrild…·T. F. De Koning-Ward
This study validates PfA-M17 as a novel drug target by showing its essential role in Plasmodium falciparum survival and demonstrating the efficacy of a specific inhibitor.
DOI 10.7554/elife.80813