Author

N. A. Counihan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:plant (other)· 2

Frequent Co-Authors

D. J. Creek· 2 shared G. Siddiqui· 2 shared S. McGowan· 2 shared T. F. de Koning-Ward· 2 shared T. R. Malcolm· 2 shared C. A. MacRaild· 1 shared C. D. Suraweera· 1 shared C. Giannangelo· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

D. J. Creek

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity.

R. C. Edgar, G. Siddiqui, T. R. Malcolm, S. Duffy, M. Chowdhury, J. Marfurt, G. Wirjanata, R. Noviyanti, K. Daware, M. Dans, C. D. Suraweera, N. A. Counihan, R. N. Price, S. Whittlin, V. M. Avery, , S. McGowan

This paper identifies MMV1557817 as a dual aminopeptidase inhibitor effective against multiple Plasmodium species and highlights its potential as a multi-target antimalarial drug.

bioRxiv · Oct 1, 2023Microbiology

Genetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway

R. C. S. Edgar, G. Siddiqui, K. Hjerrild, T. R. Malcolm, N. B. Vinh, C. T. Webb, C. A. MacRaild, N. A. Counihan, D. J. Creek, P. J. Scammels, S. McGowan, T. F. De Koning-Ward

This study validates PfA-M17 as a novel drug target by showing its essential role in Plasmodium falciparum survival and demonstrating the efficacy of a specific inhibitor.

bioRxiv · Nov 23, 2021Microbiology