T cell-specific P2RX7 favors lung parenchymal CD4+ T cell accumulation in response to severe lung infections
I. Santiago-Carvalho, G. Almeida-Santos, B. G. Macedo, C. C. B. Bomfim, F. M. Almeida, M. V. P. Cione, T. Vardam-Kaur, M. Masuda, S. van Dijk, B. M. Melo, R. S. d. Nascimento, R. d. C. Souza, A. L. Peixoto-Rangel, R. Coutinho-Silva, M. H. Hirata, , M. R. D. Lima
This study shows that T cell-specific P2RX7 promotes lung CD4+ T cell accumulation and pathology during severe lung infections like TB and influenza.
bioRxiv · Sep 19, 2022Immunology