Author

T. Vardam-Kaur

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Assay:CITE-seq· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

S. van Dijk· 3 shared B. G. Macedo· 2 shared C. Peng· 2 shared H. Borges da Silva· 2 shared I. Santiago-Carvalho· 2 shared K. M. Wanhainen· 2 shared S. C. Jameson· 2 shared A. Banuelos· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersImmunology

S. van Dijk

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The ATP-exporting channel Pannexin-1 promotes CD8+ T cell effector and memory responses

T. Vardam-Kaur, A. Banuelos, M. Gabaldon-Parish, B. G. Macedo, C. L. Salgado, K. M. Wanhainen, M. H. Zhou, S. van Dijk, I. Santiago-Carvalho, A. S. Beniwal, C. L. Leff, C. Peng, N. L. Tran, S. C. Jameson, H. Borges da Silva

This study shows that Pannexin-1 promotes CD8+ T cell effector and memory responses through distinct mechanisms involving eATP export and purinergic receptor activation.

bioRxiv · Apr 19, 2023Immunology

T cell-specific P2RX7 favors lung parenchymal CD4+ T cell accumulation in response to severe lung infections

I. Santiago-Carvalho, G. Almeida-Santos, B. G. Macedo, C. C. B. Bomfim, F. M. Almeida, M. V. P. Cione, T. Vardam-Kaur, M. Masuda, S. van Dijk, B. M. Melo, R. S. d. Nascimento, R. d. C. Souza, A. L. Peixoto-Rangel, R. Coutinho-Silva, M. H. Hirata, , M. R. D. Lima

This study shows that T cell-specific P2RX7 promotes lung CD4+ T cell accumulation and pathology during severe lung infections like TB and influenza.

bioRxiv · Sep 19, 2022Immunology

The extracellular ATP receptor P2RX7 imprints a pro-memory transcriptional signature in effector CD8+ T cells

T. Vardam-Kaur, S. van Dijk, C. Peng, K. M. Wanhainen, S. C. Jameson, H. Borges da Silva

This study shows that P2RX7 expression in effector CD8+ T cells influences their differentiation into central and resident memory cells through transcriptional changes.

bioRxiv · May 25, 2021 · PreprintImmunology