Author

R. D. Martin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Organism:rat· 2 Approach:benchmark study· 1

Frequent Co-Authors

J. C. Tanny· 2 shared J. Jones-Tabah· 2 shared T. E. Hebert· 2 shared A. Carotenuto· 1 shared A. Fournier· 1 shared A. Hernandez-Garcia· 1 shared A. Zhang· 1 shared B. G. Allen· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersPharmacology & Toxicology

J. C. Tanny

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Author profile →

4 papers

Recent·Most cited

Comparing the signaling and transcriptome profiling landscapes of human iPSC-derived and primary rat neonatal cardiomyocytes

K. Bourque, J. Jones-Tabah, D. Petrin, R. D. Martin, T. Hebert

This study compares signaling and transcriptome profiles of human iPSC-derived and primary rat cardiomyocytes to assess their suitability as models for cardiac research.

bioRxiv · Sep 6, 2022Biochemistry

Benchmark of data processing methods and machine learning models for gut microbiome-based diagnosis of inflammatory bowel disease

R. Kubinski, J.-Y. Djamen-Kepaou, T. Zhanabaev, A. Hernandez-Garcia, S. Bauer, F. Hildebrand, T. Korcsmaros, S. Karam, P. Jantchou, K. Kafi, R. D. Martin

This study benchmarks data processing methods and machine learning models for diagnosing IBD from gut microbiome data, finding that taxonomic features and non-linear models improve generalizability.

bioRxiv · May 3, 2021Microbiology

Membrane-tethered peptides derived from intracellular loops 2 and 3 of the urotensin II receptor act as allosteric biased ligands

H. Nassour, T. A. Hoang, R. D. Martin, J. C. C. Dallagnol, E. Billard, M. Letourneau, E. Novellino, A. Carotenuto, B. G. Allen, J. C. Tanny, A. Fournier, T. E. Hebert, D. Chatenet

The paper synthesizes and characterizes pepducins from the urotensin II receptor, showing they act as biased allosteric modulators with specific signaling effects.

bioRxiv · Nov 23, 2020Pharmacology & Toxicology

An interaction between Gβγ and RNA polymerase II regulates transcription in cardiac fibroblasts

S. M. Khan, R. D. Martin, S. Gora, C. Bouazza, J. Jones-Tabah, A. Zhang, S. MacKinnon, P. Trieu, P. B. Clarke, J. C. Tanny, T. E. Hebert

The paper shows Gβγ interacts with RNA polymerase II in cardiac fibroblasts, negatively regulating fibrotic gene expression, with cell-specific signaling pathways involved.

bioRxiv · Mar 13, 2020 · PreprintBiochemistry