Author

T. Korcsmaros

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2 Microbiology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 5 Organism:human· 4 Approach:statistical model· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:metabolomics· 2

Frequent Co-Authors

L. J. Hall· 3 shared S. Caim· 3 shared A. Treveil· 2 shared C. Leclaire· 2 shared D. van Sinderen· 2 shared A. Andrusaite· 1 shared A. Genna· 1 shared A. Ghanate· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

L. J. Hall

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

FAK family proteins regulate in vivo breast cancer metastasis via distinct mechanisms.

A. Genna, J. Alter, M. Poletti, T. Meirson, T. Sneh, M. Gendler, N. Saleev, G. Karagiannis, Y. Wang, D. Cox, D. Entenberg, M. Oktay, T. Korcsmaros, J. Condeelis, H. Gil-Henn

This study shows that PYK2 and FAK regulate breast cancer metastasis through distinct mechanisms, with PYK2 affecting motility and FAK reducing tumor size and metastasis.

bioRxiv · Oct 27, 2023 · PreprintCancer Biology

Invariant natural killer T-cell and CD4+ T-cell derived IL22 is a regulator of epithelial-to-mesenchymal transition and extracellular matrix remodelling in perianal fistulas

L. E. Constable, N. Iqbal, D. Cozzetto, L. Csabai, S. Anandabaskaran, T. Korcsmaros, A. Hart, P. J. Tozer, N. Powell

This study identifies IL22-producing T-cells as regulators of epithelial-to-mesenchymal transition and extracellular matrix remodelling in perianal fistulas.

bioRxiv · Sep 11, 2023 · PreprintImmunology

Benchmark of data processing methods and machine learning models for gut microbiome-based diagnosis of inflammatory bowel disease

R. Kubinski, J.-Y. Djamen-Kepaou, T. Zhanabaev, A. Hernandez-Garcia, S. Bauer, F. Hildebrand, T. Korcsmaros, S. Karam, P. Jantchou, K. Kafi, R. D. Martin

This study benchmarks data processing methods and machine learning models for diagnosing IBD from gut microbiome data, finding that taxonomic features and non-linear models improve generalizability.

bioRxiv · May 3, 2021Microbiology

Evolution of regulatory networks associated with traits under selection in cichlids

T. K. Mehta, C. Koch, W. Nash, S. A. Knaack, P. Sudhakar, M. Olbei, S. Bastkowski, L. Penso-Dolfin, T. Korcsmaros, W. Haerty, S. Roy, F. Di-Palma

The paper reconstructs gene regulatory networks in cichlids to study GRN evolution linked to adaptive traits, identifying regulatory variants and network rewiring in visual opsin genes.

bioRxiv · Apr 17, 2020Evolutionary Biology

Bifidobacterium breve UCC2003 exopolysaccharide modulates the early life microbiota by acting as a dietary substrate

D. Puengel, A. Treveil, M. J. Dalby, S. Caim, I. J. Colquhoun, C. Booth, J. Ketskemety, T. Korcsmaros, D. van Sinderen, M. A. Lawson, L. J. Hall

This study shows that Bifidobacterium breve UCC2003 exopolysaccharide (EPS) alters infant microbiota and metabolite profiles by serving as a nutrient substrate.

Nutrients · Mar 29, 2020Peer-reviewedMicrobiology

Bifidobacterium breve UCC2003 induces a distinct global transcriptomic programme in neonatal murine intestinal epithelial cells

R. Kiu, A. Treveil, L. C. Harnisch, S. Caim, C. Leclaire, D. van Sinderen, T. Korcsmaros, L. J. Hall

This study shows that Bifidobacterium breve UCC2003 significantly alters the transcriptome of neonatal intestinal epithelial cells, enhancing cell replication, differentiation, and growth.

bioRxiv · Mar 27, 2020Immunology

Perturbation of the gut microbiota by antibiotics results in accelerated breast tumour growth and metabolic dysregulation

B. Kirkup, A. McKee, K. Makin, J. Paveley, S. Caim, C. Alcon-Giner, C. Leclaire, M. Dalby, G. Le Gall, A. Andrusaite, P. Kreuzaler, P. Driscoll, J. MacRae, E. Calvani, A. Ghanate, , S. D. Robinson

This study shows that antibiotics disrupt the gut microbiota, leading to faster breast tumour growth and metabolic changes in mice.

bioRxiv · Feb 19, 2019 · PreprintCancer Biology