Author

S. Mackinnon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Organism:Drosophila· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

A. G. Goodman· 1 shared A. Zhang· 1 shared B. K. Torrevillas· 1 shared C. Bouazza· 1 shared C. E. Trammell· 1 shared C. Y. Chow· 1 shared D. S. Froese· 1 shared G. F. Carrell· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperMicrobiology

A. G. Goodman

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Author profile →

3 papers

Recent·Most cited

Naturally occurring cobalamin (B12) analogs can function as cofactors for human methylmalonyl-CoA mutase

O. M. Sokolovskaya, T. Plessl, H. Bailey, S. Mackinnon, M. R. Baumgartner, W. W. Yue, D. S. Froese, M. E. Taga

The paper investigates how different cobamides affect the function of methylmalonyl-CoA mutase and shows that non-cobalamin cobamides can also support its activity.

bioRxiv · Mar 20, 2020Biochemistry

An interaction between Gβγ and RNA polymerase II regulates transcription in cardiac fibroblasts

S. M. Khan, R. D. Martin, S. Gora, C. Bouazza, J. Jones-Tabah, A. Zhang, S. MacKinnon, P. Trieu, P. B. Clarke, J. C. Tanny, T. E. Hebert

The paper shows Gβγ interacts with RNA polymerase II in cardiac fibroblasts, negatively regulating fibrotic gene expression, with cell-specific signaling pathways involved.

bioRxiv · Mar 13, 2020 · PreprintBiochemistry

Insulin potentiates JAK/STAT signaling to broadly inhibit flavivirus replication in insect vectors

L. R. H. Ahlers, C. E. Trammell, G. F. Carrell, S. Mackinnon, B. K. Torrevillas, C. Y. Chow, S. Luckhart, A. G. Goodman

This study identifies insulin-like receptor as a novel immune component in insects, showing insulin signaling inhibits flavivirus replication via JAK/STAT pathway activation in Drosophila and mosquitoes.

bioRxiv · Jul 13, 2019Microbiology