Author

R. D. Zeinert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:C. elegans· 3 Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 3 Organism:bacteria (other)· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

P. Chien· 5 shared B. B. Barros· 2 shared B. Tu· 1 shared B. Zhao· 1 shared C. Haynes· 1 shared H. Baniasadi· 1 shared J. Liu· 1 shared J. Ogdahl· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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5 shared papersMicrobiology

P. Chien

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Author profile →

5 papers

Recent·Most cited

Proteomic survey of the DNA damage response in Caulobacter crescentus

T. F. Tashjian, R. D. Zeinert, S. J. Eyles, P. Chien

This study performs a proteomic survey of the DNA damage response in Caulobacter crescentus, identifying novel factors and dynamics not captured by transcriptional studies.

bioRxiv · Mar 24, 2023 · PreprintMicrobiology

A legacy role for DNA binding of Lon protects against genotoxic stress

R. D. Zeinert, J. Ogdahl, J. Liu, Q. Yang, Y. Du, B. B. Barros, P. L. Freddolino, C. Haynes, P. Chien

The paper shows that Lon protease DNA binding protects bacteria and mitochondria from genotoxic stress by clearing bound proteins.

bioRxiv · Dec 27, 2022 · PreprintMicrobiology

Live-Cell Imaging of (p)ppGpp with RNA-based Fluorescent Sensors

Z. Sun, R. Wu, B. Zhao, R. D. Zeinert, P. Chien, M. You

This paper develops RNA-based fluorescent sensors to directly image and measure (p)ppGpp in live bacterial cells, revealing cell-to-cell variation and dynamics under different nutritional conditions.

bioRxiv · May 12, 2021 · PreprintCell Biology

Degradation of Lon in Caulobacter crescentus

B. B. Barros, S. A. Mahmoud, P. Chien, R. D. Zeinert

This study shows that Lon protease levels in Caulobacter crescentus are controlled by proteolysis involving Lon and ClpAP, with a carboxy-terminal histidine residue critical for recognition.

bioRxiv · Jun 12, 2020Microbiology

The Lon protease links nucleotide metabolism with proteotoxic stress

R. D. Zeinert, H. Baniasadi, B. Tu, P. Chien

This study shows that the Lon protease in Caulobacter crescentus regulates dNTP pools by degrading CcrM, linking nucleotide metabolism with proteotoxic stress response.

bioRxiv · Dec 10, 2019Microbiology