Author

R. Eapen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

L. S. Itzhaki· 2 shared A. Perez-Riba· 1 shared A. Weissl· 1 shared C. Lindon· 1 shared C. Okoye· 1 shared C. Phillips· 1 shared C. Stubbs· 1 shared D. Barford· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

L. S. Itzhaki

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2 papers

Recent·Most cited

Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome

R. Eapen, C. Okoye, C. Stubbs, M. Schimpl, T. Tischer, E. J. Fisher, M. Zacharopoulou, F. Ferrer, D. Barford, D. Spring, C. Lindon, C. Phillips, L. S. Itzhaki

This study develops D-box peptides that inhibit APC/C by binding Cdc20, showing they are more potent than Apcin and can drive protein degradation.

bioRxiv · Apr 30, 2024Biochemistry

Consensus tandem tetratricopeptide repeat proteins are complex superhelical nanosprings

M. Synakewicz, R. Eapen, A. Perez-Riba, D. Bauer, A. Weissl, G. Fischer, M. Hyvonen, M. Rief, L. S. Itzhaki, J. Stigler

This study investigates the mechanical properties of consensus-designed tetratricopeptide repeats (CTPRs) using single-molecule techniques, revealing their spring-like behavior and superhelical structure.

bioRxiv · Mar 27, 2021Biophysics