Author

R. Eastman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:virus· 1

Frequent Co-Authors

A. Simeonov· 2 shared P. Shinn· 2 shared R. Huang· 2 shared A. V. Zakharov· 1 shared A. Yasgar· 1 shared B. Brooks· 1 shared C. Klumpp-Thomas· 1 shared C. Lynch· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. Simeonov

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2 papers

Recent·Most cited

Quantitative bioactivity signatures of dietary supplements and natural products

A. Yasgar, D. Bougie, C. McKnight, M. Miller, T. Peryea, M. Xia, P. Shah, X. Xu, P. Shinn, M. Itkin, C. Lynch, A. V. Zakharov, R. Eastman, J. Kouznetsova, D. Ngan, , A. Simeonov

The paper screens dietary supplements and natural products for bioactivity using in vitro assays and predicts their mechanisms of action by comparing activity profiles with approved drugs.

bioRxiv · Sep 14, 2022Pharmacology & Toxicology

Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2

C. Z. Chen, P. Shinn, Z. Itkin, R. Eastman, R. Bostwick, L. Rasmussen, R. Huang, M. Shen, X. Hu, K. M. Wilson, B. Brooks, H. Guo, T. Zhao, C. Klumpp-Thomas, A. Simeonov, , W. Zheng

The paper identifies 319 compounds with anti-SARS-CoV-2 activities through a high-throughput screen, including 91 approved drugs and 49 investigational drugs, with 230 compounds previously unreported.

bioRxiv · Aug 18, 2020Microbiology