Author

R. Foisner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Pennanen· 1 shared C. Butler-Hallissey· 1 shared C. Knapp· 1 shared C.-G. A. Stenvall· 1 shared D. M. Toivola· 1 shared E. Sidorenko· 1 shared E. Zier· 1 shared E.-Y. K. Choi· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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1 shared paperCell Biology

A. Pennanen

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Author profile →

4 papers

Recent·Most cited

Hepatocyte-specific loss of LAP2α protects against diet-induced hepatic steatosis and steatohepatitis in male mice

K. K. Upadhyay, E.-Y. K. Choi, R. Foisner, M. B. Omary, G. F. Brady

This study shows that deleting Lap2a in mouse hepatocytes reduces diet-induced hepatic steatosis and NASH compared to controls.

bioRxiv · Mar 18, 2022 · PreprintPhysiology

Lamina-associated polypeptide 2α is required for intranuclear MRTF-A activity

E. Sidorenko, M. Sokolova, A. Pennanen, S. Kyheroinen, G. Posern, R. Foisner, M. Vartiainen

This study identifies Lap2 as a novel regulator of MRTF-A activity, showing it is required for efficient expression of MRTF-A/SRF target genes and serum-induced cell migration.

bioRxiv · Jan 8, 2021Cell Biology

LAP2alpha maintains a mobile and low assembly state of A-type lamins in the nuclear interior

N. Naetar, K. Georgiou, C. Knapp, I. Bronshtein, E. Zier, P. Fichtinger, T. Dechat, Y. Garini, R. Foisner

This study shows LAP2alpha prevents the formation of stable lamin A/C structures in the nuclear interior, maintaining their mobility and preventing chromatin immobilization.

bioRxiv · Sep 25, 2020Cell Biology

Keratins couple with the nuclear lamina and regulate proliferation in colonic epithelial cells

C.-G. A. Stenvall, J. H. Nyström, C. Butler-Hallissey, S. A. Adam, R. Foisner, K. M. Ridge, R. D. Goldman, D. M. Toivola

This study shows that keratin 8 (K8) in colonic epithelial cells couples with the nuclear lamina, regulates proliferation through pRb and YAP, and its loss leads to hyperproliferation and reduced lamins.

bioRxiv · Jun 22, 2020Cell Biology