Author

K. M. Ridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

A. V. Misharin· 3 shared G. S. Budinger· 3 shared H. Abdala-Valencia· 3 shared A. Bharat· 2 shared D. R. Winter· 2 shared J. I. Sznajder· 2 shared J. M. Davis· 2 shared P. A. Reyfman· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersImmunology

A. V. Misharin

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Expansion of profibrotic monocyte-derived alveolar macrophages in patients with persistent respiratory symptoms and radiographic abnormalities after COVID-19

J. I. Bailey, C. H. Puritz, K. J. Senkow, N. S. Markov, E. Diaz, E. Jonasson, Z. Yu, S. Swaminathan, Z. Lu, S. Fenske, R. A. Grant, H. Abdala-Valencia, R. J. Mylvaganam, J. Miller, R. I. Cumming, , M. A. Sala

The paper identifies profibrotic monocyte-derived alveolar macrophages and neutrophil recruitment as drivers of lung fibrosis in patients with persistent respiratory symptoms and radiographic abnormalities after COVID-19.

bioRxiv · Jul 30, 2023Immunology

Gigaxonin is required for intermediate filament transport

B. Renganathan, J. P. Zewe, Y. Cheng, M. Kittisopikul, P. Opal, K. M. Ridge, V. I. Gelfand

This study shows that gigaxonin is essential for intermediate filament transport by kinesin-1, and its loss leads to IF accumulation due to increased soluble vimentin oligomers.

bioRxiv · Aug 19, 2022Cell Biology

Keratins couple with the nuclear lamina and regulate proliferation in colonic epithelial cells

C.-G. A. Stenvall, J. H. Nyström, C. Butler-Hallissey, S. A. Adam, R. Foisner, K. M. Ridge, R. D. Goldman, D. M. Toivola

This study shows that keratin 8 (K8) in colonic epithelial cells couples with the nuclear lamina, regulates proliferation through pRb and YAP, and its loss leads to hyperproliferation and reduced lamins.

bioRxiv · Jun 22, 2020Cell Biology

Influenza-induced activation of recruited alveolar macrophages during the early inflammatory phase drives lung injury and lethality

C. M. Koch, K. Anekalla, Y.-S. Hu, J. M. Davis, M. Ciesielski, G. Gadhvi, S.-Y. Chen, M. Turner, Y. Cheng, B. M. Coates, H. Abdala-Valencia, P. A. Reyfman, A. V. Misharin, G. S. Budinger, D. R. Winter, K. M. Ridge

This study identifies vimentin's role in driving pro-inflammatory responses in alveolar macrophages during influenza infection, linking it to lung injury and mortality.

bioRxiv · Jun 8, 2020 · PreprintImmunology

The Aging Microenvironment Shapes Alveolar Macrophage Identity in Aging

A. C. McQuattie-Pimentel, Z. Ren, N. Joshi, S. Watanabe, T. Stoeger, M. Chi, Z. Lu, L. Sichizya, R. Piseaux, C.-I. Chen, S. Soberanes, P. A. Reyfman, J. M. Walter, K. R. Anekalla, J. M. Davis, , G. S. Budinger

This study shows that the aging lung microenvironment shapes alveolar macrophage identity, influencing their phenotype during aging and after injury.

bioRxiv · Jul 29, 2019 · PreprintImmunology