R. Gaudet

They all rock: A systematic comparison of conformational movements in LeuT-fold transporters

The paper systematically compares conformational movements in LeuT-fold transporters using distance difference matrices, identifying common and distinct motions across nine proteins.

Structure of an insect gustatory receptor

The paper determines the structure of BmGr9, an insect gustatory receptor, and compares it to olfactory receptors to understand ligand specificity.

High-resolution structures map the metal import pathway in an Nramp transporter

The paper presents high-resolution structures of the Nramp transporter from Deinococcus radiodurans in different conformations, revealing insights into metal coordination and transport mechanisms.

Natural transformation protein ComFA exhibits single-stranded DNA translocase activity

This study investigates ComFA's role in natural transformation by demonstrating its single-stranded DNA translocase activity and ATP-dependent DNA release mechanism.

Selecting for altered substrate specificity reveals the evolutionary flexibility of ATP-binding cassette transporters

This study mutagenizes and selects for altered substrate specificity in an ABC transporter to explore evolutionary flexibility in substrate selectivity.

Transmembrane helix 6b links proton- and metal-release pathways to drive conformational change in an Nramp transition metal transporter

This study identifies transmembrane helix 6b as critical for conformational changes in the Nramp transporter, linking metal and proton release pathways.

Interaction specificity of clustered protocadherins inferred from sequence covariation and structural analysis

The paper uses sequence coevolution and structural analysis to model interaction specificity of clustered protocadherins and predict isoform-specific interactions.

Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter

The paper presents high-resolution structures of DraNramp at different stages of its transport cycle to elucidate metal and proton pathways and conformational changes in the Nramp transporter.

Proton co-transport and voltage dependence enforce unidirectional metal transport in an Nramp transporter

The paper investigates the mechanism of metal transport in an Nramp transporter, revealing that proton co-transport and voltage dependence enforce unidirectional metal movement.