Author

R. Guzik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Marchel· 2 shared B. Gielniewski· 2 shared B. Kaminska· 2 shared B. Wojtas· 2 shared S. K. Krol· 2 shared T. Czernicki· 2 shared A. Dziedzic· 1 shared A. Koziarski· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

A. Marchel

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2 papers

Recent·Most cited

The novel, recurrent mutation in the TOP2A gene results in the enhanced topoisomerase activity and transcription deregulation in glioblastoma

B. Gielniewski, K. Poleszak, A.-J. Roura, P. Szadkowska, S. K. Krol, R. Guzik, P. Wiechecka, M. Maleszewska, B. Kaza, A. Marchel, T. Czernicki, A. Koziarski, G. Zielinski, A. Styk, M. Kawecki, , B. Kaminska

The paper identifies a novel TOP2A mutation in glioblastomas that enhances DNA binding and transcriptional activity, correlating with poorer patient survival.

bioRxiv · Jun 17, 2020 · PreprintCancer Biology

Mapping chromatin accessibility and active regulatory elements reveals new pathological mechanisms in human gliomas

K. Stepniak, M. A. Machnicka, J. Mieczkowski, A. Macioszek, B. Wojtas, B. Gielniewski, S. K. Krol, R. Guzik, M. J. Dabrowski, M. Draminski, M. Jardanowska, I. Grabowicz, A. Dziedzic, H. Kranas, K. Sienkiewicz, , B. Wilczynski

The paper maps chromatin accessibility and regulatory elements in human gliomas to identify new epigenetic mechanisms driving cancer progression.

bioRxiv · Mar 20, 2020Cancer Biology