Author

R. Holmes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Pritchard· 1 shared B. K. Chacko· 1 shared B. R. Levin· 1 shared D. Chanda· 1 shared J. Chin· 1 shared J. G. Strenkowski· 1 shared J. L. Trevor· 1 shared J. L. Weissman· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. Pritchard

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Small Extracellular Vesicle Signaling and Mitochondrial Transfer Reprograms T Helper Cell Function in Human Asthma

K. P. Hough, J. L. Trevor, S. Ahmad, Y. Wang, B. K. Chacko, K. F. Goliwas, J. G. Strenkowski, N. B. Bone, Y.-i. Kim, R. Holmes, Y. Liu, S. Vang, A. Pritchard, J. Chin, S. Bodduluri, , J. S. Deshane

This study shows that mitochondrial-containing sEVs from MDRCs activate and polarize Th17 and Th2 cells in asthma, contributing to airway inflammation.

bioRxiv · Apr 30, 2024Immunology

Immune Loss as a Driver of Coexistence During Host-Phage Coevolution

J. L. Weissman, R. Holmes, R. Barrangou, S. Moineau, W. F. Fagan, B. R. Levin, P. L. Johnson

The paper shows that immune loss in bacteria can lead to stable coexistence with phages, contrasting with fitness tradeoffs, through theoretical and experimental analysis of CRISPR-Cas systems.

bioRxiv · Sep 18, 2017Ecology