Author

R. J. Allaway

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 3 Organism:human· 3 Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:benchmark study· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

J. Guinney· 4 shared A. Schlessinger· 2 shared F. Wan· 2 shared J. Kang· 2 shared J. Zeng· 2 shared M. Jeon· 2 shared S. Li· 2 shared X. Guo· 2 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersCancer Biology

J. Guinney

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4 papers

Recent·Most cited

Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: the Multi-Targeting Drug DREAM Challenge

Z. Xiong, M. Jeon, R. J. Allaway, J. Kang, D. Park, J. Lee, H. Jeon, M. Ko, H. Jiang, M. Zheng, A. C. Tan, X. Guo, The Multi-Targeting Drug DREAM Challenge Community, K. K. Dang, A. Tropsha, , R. Cagan

The paper reports on a DREAM Challenge to predict multi-target kinase inhibitors for RET-based tumors and Tauopathy, using neural network-based machine learning approaches.

bioRxiv · Feb 15, 2021Pharmacology & Toxicology

A Community Challenge for Pancancer Drug Mechanism of Action Inference from Perturbational Profile Data

E. F. Douglass, R. J. Allaway, B. Szalai, W. Wang, T. Tian, A. Fernandez-Torras, R. Realubit, C. Karan, S. Zheng, A. Pessia, Z. Tanoli, M. Jafari, F. Wan, S. Li, Y. Xiong, , A. Califano

The paper hosts a DREAM Challenge to evaluate computational models for predicting drug polypharmacology using perturbational profile data from 32 kinase inhibitors.

bioRxiv · Dec 21, 2020Cancer Biology

Crowdsourced mapping of unexplored target space of kinase inhibitors

A. Cichonska, B. Ravikumar, R. J. Allaway, S. Park, F. Wan, O. Isayev, S. Li, M. J. Mason, A. Lamb, Z.-u.-R. Tanoli, M. Jeon, S. Kim, M. Popova, S. Capuzzi, J. Zeng, , T. Aittokallio

The paper benchmarks predictive models for kinase inhibitor potencies using crowdsourced data and identifies new compound-kinase interactions.

bioRxiv · Dec 31, 2019Biochemistry

A clinically and genomically annotated nerve sheath tumor biospecimen repository.

K. Pollard, J. Banerjee, X. Doan, J. Wang, X. Guo, R. J. Allaway, S. Langmead, B. Slobogean, C. Meyer, D. Loeb, C. Morris, A. Belzberg, J. O. Blakeley, F. Rodriguez, J. Guinney, , C. A. Pratilas

The paper establishes a clinically and genomically annotated nerve sheath tumor biospecimen repository to support research on NF1-related tumors.

bioRxiv · Dec 19, 2019Cancer Biology