Author

R. J. Morscher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

S. Cherkaoui· 2 shared A. Cremonesi· 1 shared A. Gosh· 1 shared A. Vu· 1 shared C. Eigenmann· 1 shared C. Turn· 1 shared E. Masschelein· 1 shared E. White· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

S. Cherkaoui

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Author profile →

2 papers

Recent·Most cited

Reprogramming neuroblastoma by diet-enhanced polyamine depletion

S. Cherkaoui, L. Yang, M. J. McBride, C. Turn, W. Lu, C. Eigenmann, G. E. Allen, O. O. Panasenko, L. Zhang, A. Vu, K. Liu, Y. Li, O. H. Gandhi, L. Surrey, M. Wierer, , R. J. Morscher

This paper shows that combining dietary restriction of arginine and proline with polyamine depletion drugs enhances tumor differentiation and survival in a neuroblastoma mouse model by disrupting oncogenic translation.

bioRxiv · Jan 7, 2024Cancer Biology

GLUD1 dictates muscle stem cell differentiation by controlling mitochondrial glutamate levels

I. Soro-Arnaiz, S. Cherkaoui, G. Fitzgerald, J. Zhang, P. Gilardoni, A. Gosh, O. Bar-Nur, E. Masschelein, P. Maechler, N. Zamboni, M. Poms, A. Cremonesi, J. C. Garcia-Canaveras, K. De Bock, R. J. Morscher

This study shows that GLUD1 controls muscle stem cell differentiation by regulating mitochondrial glutamate levels and the malate-aspartate shuttle.

bioRxiv · Oct 4, 2023 · PreprintCell Biology