Author

A. I. Perault

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Organism:bacteria (other)· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

P. A. Cotter· 2 shared A. DuMont· 1 shared A. F. Haag· 1 shared A. Pironti· 1 shared A. Pountain· 1 shared A. R. Richardson· 1 shared B. Shopsin· 1 shared C. A. Hodges· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersMicrobiology

P. A. Cotter

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3 papers

Recent·Most cited

Quorum-sensing agr system of Staphylococcus aureus primes gene expression for protection from lethal oxidative stress

M. Podkowik, A. I. Perault, G. Putzel, A. Pountain, J. Kim, A. DuMont, E. Zwack, R. J. Ulrich, T. K. Karagounis, C. Zhou, A. F. Haag, J. Shenderovich, G. A. Wasserman, J. Kwon, J. Chen, , B. Shopsin

This study shows that the agr quorum-sensing system in Staphylococcus aureus primes the bacteria to resist oxidative stress by controlling reactive oxygen species, even when the system is not actively activated.

bioRxiv · Jun 8, 2023 · PreprintMicrobiology

The Burkholderia cenocepacia type VI secretion system effector TecA is a virulence factor during lung infection

N. A. Loeven, A. I. Perault, P. A. Cotter, C. A. Hodges, J. D. Schwartzman, T. H. Hampton, J. B. Bliska

This paper demonstrates that TecA, a type VI secretion system effector of Burkholderia cenocepacia, acts as a virulence factor by exacerbating lung inflammation, weight loss, and lethality in a CF mouse model.

bioRxiv · Jul 13, 2021Microbiology

Host Adaptation Predisposes Pseudomonas aeruginosa to Type VI Secretion System-Mediated Predation by the Burkholderia cepacia Complex

A. I. Perault, C. E. Chandler, D. A. Rasko, R. K. Ernst, M. C. Wolfgang, P. A. Cotter

The paper shows that Pa isolates from older CF patients are outcompeted by Bcc strains due to T6SS-abrogating mutations, increasing susceptibility to Bcc superinfection.

Cell Host & Microbe · Oct 1, 2020Peer-reviewedMicrobiology