Author

R. Jara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Rojas-Fernandez· 2 shared D. Schwefel· 2 shared P. Chana-Cuevas· 2 shared A. A. Amarilla· 1 shared A. A. Khromykh· 1 shared A. Isaacs· 1 shared A. Kjaer· 1 shared B. Liang· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBiochemistry

A. Rojas-Fernandez

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Author profile →

2 papers

Recent·Most cited

Specific proteolysis mediated by a p97-directed proteolysis-targeting chimera (PROTAC)

C. Salinas-Rebolledo, J. Blesa, G. Valenzuela-Nieto, D. Schwefel, N. Lopez Gonzalez del Rey, M. Mendez-Ruette, J. Burkhalter, L. F. Batiz, R. Jara, J. A. Obeso, P. Chana-Cuevas, G. P. Sapkota, A. Rojas-Fernandez

This paper describes the engineering of a PROTAC that uses p97-directed proteolysis to achieve specific substrate degradation without relying on E3 ubiquitin ligases.

bioRxiv · Mar 8, 2024Biochemistry

An alpaca-derived nanobody neutralizes the SARS-CoV-2 omicron variant

N. Modhiran, S. M. Lauer, A. A. Amarilla, P. Hewins, S. I. L. van den Broek, Y. S. Low, N. Thakur, B. Liang, G. V. Nieto, J. Jung, D. Paramitha, A. Isaacs, J. de Sng, D. Song, J. Jorgensen, , D. Watterson

This paper identifies a nanobody that effectively neutralizes the SARS-CoV-2 Omicron variants BA.1 and BA.2, showing high affinity and pre-clinical promise.

bioRxiv · Dec 27, 2022 · PreprintMicrobiology