Author

A. Isaacs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

D. Watterson· 3 shared A. A. Amarilla· 2 shared A. A. Khromykh· 2 shared B. Liang· 2 shared K. Chappell· 2 shared N. Modhiran· 2 shared P. R. Young· 2 shared A. Azuar· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

D. Watterson

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

An alpaca-derived nanobody neutralizes the SARS-CoV-2 omicron variant

N. Modhiran, S. M. Lauer, A. A. Amarilla, P. Hewins, S. I. L. van den Broek, Y. S. Low, N. Thakur, B. Liang, G. V. Nieto, J. Jung, D. Paramitha, A. Isaacs, J. de Sng, D. Song, J. Jorgensen, , D. Watterson

This paper identifies a nanobody that effectively neutralizes the SARS-CoV-2 Omicron variants BA.1 and BA.2, showing high affinity and pre-clinical promise.

bioRxiv · Dec 27, 2022 · PreprintMicrobiology

Type IV pili is a critical virulence factor in clinical isolates of Paenibacillus thiaminolyticus

C. Hehnly, A. Shi, P. Ssentongo, L. Zhang, A. Isaacs, S. U. Morton, N. Streck, P. Erdmann-Gilmore, I. Tolstoy, R. R. Townsend, D. D. Limbrick, J. N. Paulson, J. E. Ericson, M. Y. Galperin, S. J. Schiff, J. R. Broach

The paper identifies type IV pili as a critical virulence factor in Paenibacillus thiaminolyticus clinical isolates associated with postinfectious hydrocephalus.

bioRxiv · Jan 24, 2022 · PreprintMicrobiology

Complete protection by a single dose skin patch delivered SARS-CoV-2 spike vaccine

C. L. D. McMillan, J. J. Y. Choo, A. Idris, A. Supramaniam, N. Modhiran, A. A. Amarilla, A. Isaacs, S. T. M. Cheung, B. Liang, H. Bielefeldt-Ohmann, A. Azuar, D. Acharya, G. Kelly, G. J. P. Fernando, M. J. Landsberg, , D. A. Muller

A single dose of a SARS-CoV-2 spike vaccine delivered via a high-density microarray patch provides complete protection against a lethal virus challenge.

bioRxiv · May 30, 2021Microbiology

Concerns regarding vaccination as a management strategy against koala retrovirus

B. A. Joyce, D. Watterson, A. Isaacs, K. Chappell

This paper challenges the effectiveness of a recombinant vaccine against KoRV by showing undetectable anti-Env antibodies in infected koalas, suggesting potential flaws in prior studies.

bioRxiv · May 10, 2021 · PreprintImmunology