Author

G. L. Horvath

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

E. Latz· 2 shared A. Akbal· 1 shared A. Schroeder· 1 shared B. G. Monks· 1 shared C. S. Forconi· 1 shared D. R. Caffrey· 1 shared D. T. Golenbock· 1 shared D. Wachten· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

E. Latz

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2 papers

Recent·Most cited

Cytosolic sodium accumulation is a common danger signal triggering endocytic dysfunction and NLRP3 inflammasome activation

M. S. J. Mangan, A. Akbal, S. Rivara, A. Schroeder, G. L. Horvath, P. Walch, J. Hegermann, R. Kaiser, F. Duthie, J. Selkrig, J. Jantsch, R. Gerhard, D. Wachten, E. Latz

The paper shows that cytosolic sodium accumulation triggers NLRP3 inflammasome activation in response to various danger signals in human macrophages.

bioRxiv · Mar 26, 2024 · PreprintImmunology

Epigenetic regulation of innate immune genes and enhanced interleukin-10 expression underlie chronic subclinical Plasmodium chabaudi infection

L. de Souza Silva, Y. A. H. Nguyen, B. G. Monks, C. S. Forconi, J. N. Crabtree, T. Rodriguez, N. D. P. Tamburro, E. J. Sontheimer, G. L. Horvath, Z. Abdullah, E. Latz, D. R. Caffrey, E. Kurt-Jones, R. T. Gazzinelli, K. A. Fitzgerald, D. T. Golenbock

This study identifies epigenetic regulation of innate immune genes and increased IL-10 expression as mechanisms underlying chronic subclinical Plasmodium chabaudi infection in mice.

bioRxiv · Feb 23, 2023 · PreprintImmunology