Virulence and genomic diversity among clinical isolates of ST1 (BI/NAP1/027) Clostridioides difficile
Q. Dong, H. Lin, M.-M. Allen, J. R. Garneau, J. K. Sia, R. C. Smith, F. Haro, T. McMillen, R. L. Pope, C. Metcalfe, V. Burgo, C. Woodson, N. Dylla, C. Kohout, A. Sundararajan, , E. G. Pamer
This study identifies a 69 base-pair deletion in the cdtR gene that attenuates virulence in ST1 C. difficile strains without affecting colonization.
bioRxiv · Jan 12, 2023Microbiology