Author

J. K. Sia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

E. G. Pamer· 2 shared E. S. Snitkin· 2 shared H. Lin· 2 shared M. Kamboj· 2 shared Q. Dong· 2 shared V. B. Young· 2 shared A. Shen· 1 shared A. Sundararajan· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersMicrobiology

E. G. Pamer

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2 papers

Recent·Most cited

Flagellar switch inverted repeat impacts flagellar invertibility and varies Clostridioides difficile RT027/MLST1 virulence.

N. T. Q. Nhu, H. Lin, Y. Pigli, J. K. Sia, P. Kuhn, E. S. Snitkin, V. B. Young, M. Kamboj, E. G. Pamer, P. A. Rice, A. Shen, Q. Dong

The paper identifies that longer inverted repeats in the flagellar switch region of C. difficile RT027 strains correlate with greater virulence and phenotypic heterogeneity in flagellar gene expression.

bioRxiv · Jun 22, 2023 · PreprintMicrobiology

Virulence and genomic diversity among clinical isolates of ST1 (BI/NAP1/027) Clostridioides difficile

Q. Dong, H. Lin, M.-M. Allen, J. R. Garneau, J. K. Sia, R. C. Smith, F. Haro, T. McMillen, R. L. Pope, C. Metcalfe, V. Burgo, C. Woodson, N. Dylla, C. Kohout, A. Sundararajan, , E. G. Pamer

This study identifies a 69 base-pair deletion in the cdtR gene that attenuates virulence in ST1 C. difficile strains without affecting colonization.

bioRxiv · Jan 12, 2023Microbiology