Author

R. Leach

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. J. Link· 1 shared A. Thokkadam· 1 shared C. McKinley· 1 shared C. S. McKimmie· 1 shared D. J. Newton· 1 shared D. J. Payne· 1 shared G. P. Cook· 1 shared K. Riley· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

A. J. Link

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The Anti-Burkholderia Lasso Peptide Ubonodin Co-Opts the Siderophore Receptor PupB for Cellular Entry

T. Do, A. Thokkadam, R. Leach, A. J. Link

This study identifies PupB as an outer membrane receptor required for ubonodin uptake in Burkholderia cepacia, revealing that transport, not target inhibition, determines its activity.

bioRxiv · Mar 9, 2022 · PreprintMicrobiology

The CXCR6/CXCL16 axis links inflamm-aging to disease severity in COVID-19 patients

D. J. Payne, S. Dalal, R. Leach, R. Parker, S. Griffin, C. S. McKimmie, G. P. Cook, S. J. Richards, P. Hillmen, T. Munir, L. Arnold, K. Riley, C. McKinley, S. Place, R. L. Baretto, D. J. Newton

This study examines the role of the CXCR6/CXCL16 axis in severe COVID-19, finding elevated CD8+CXCR6+ T cells with age and increased CXCL16 levels in severe cases.

bioRxiv · Jan 25, 2021 · PreprintImmunology