The organizer of chromatin topology RIF1 ensures cellular resilience to DNA replication stress.
C. Ribeyre, R. Lebdy, J. Patouillard, M. Larroque, R. Abou-Merhi, C. Larroque, A. Constantinou
This study shows RIF1 stabilizes chromatin topology to reduce DNA replication stress-induced genomic instability.
bioRxiv · Oct 22, 2021Cell Biology