Author

L. Chaloin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Aze· 1 shared A. Constantinou· 1 shared A. Pruvost· 1 shared B. Kim· 1 shared C. Arpin-Andre· 1 shared C. Goujon· 1 shared C. Ribeyre· 1 shared C. Shepard· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Aze

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The N-terminal domain of MX1 proteins is essential for their antiviral activity against different families of RNA viruses

J. McKellar, M. Arnaud-Arnould, L. Chaloin, M. Tauziet, C. Arpin-Andre, O. Pourcelot, M. Blaise, O. Moncorge, C. Goujon

This study identifies the N-terminal domain of HsMX1 as essential for antiviral activity against IAV and VSV, with a conserved leucine crucial for function.

bioRxiv · May 10, 2022 · PreprintMicrobiology

Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites.

J. Basbous, A. Aze, L. Chaloin, R. Lebdy, D. Hodroj, C. Ribeyre, M. Larroque, C. Shepard, B. Kim, A. Pruvost, J. Moreaux, D. Maiorano, M. Mechali, A. Constantinou

This study shows dihydropyrimidines are cytotoxic metabolites that cause DNA replication stress and DPCs, suggesting DHP inhibition could target solid tumors.

bioRxiv · Mar 5, 2019Cancer Biology