Author

M. Mechali

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

D. Maiorano· 2 shared A. Aze· 1 shared A. Constantinou· 1 shared A. Pruvost· 1 shared B. Kim· 1 shared C. Ribeyre· 1 shared C. Shepard· 1 shared D. Hodroj· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

D. Maiorano

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Author profile →

2 papers

Recent·Most cited

Identification and Characterisation of Proteins Binding to a G-Quadruplex Origin G-rich Repeated Element in Mammalian Cells

J. R. A. Hutchins, I. Peiffer, S. Urbach, J.-L. Mergny, P. Marin, D. Maiorano, M. MECHALI

The paper identifies proteins that bind to an OGRE element in mammalian cells and shows their role in DNA synthesis by affecting the cell cycle.

bioRxiv · Mar 30, 2023 · PreprintCell Biology

Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites.

J. Basbous, A. Aze, L. Chaloin, R. Lebdy, D. Hodroj, C. Ribeyre, M. Larroque, C. Shepard, B. Kim, A. Pruvost, J. Moreaux, D. Maiorano, M. Mechali, A. Constantinou

This study shows dihydropyrimidines are cytotoxic metabolites that cause DNA replication stress and DPCs, suggesting DHP inhibition could target solid tumors.

bioRxiv · Mar 5, 2019Cancer Biology