Author

R. Levin-Klein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

P. Argyris· 3 shared R. Harris· 3 shared E. Law· 2 shared M. Carpenter· 2 shared A. Aguilera· 1 shared A. Alonso· 1 shared A. Holzhauer· 1 shared A. Molan· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCancer Biology

P. Argyris

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3 papers

Recent·Most cited

Human APOBEC3B promotes tumor heterogeneity in vivo including signature mutations and metastases

C. Durfee, N. A. Temiz, R. Levin-Klein, P. Argyris, L. Alsoe, S. Carracedo, A. Alonso, J. Proehl, A. Holzhauer, Z. Seeman, Y.-H. T. Lin, R. I. Vogel, R. Sotillo, H. Nilsen, R. Harris

This study shows that human APOBEC3B causes tumor heterogeneity and metastases in mice, with increased C-to-T mutations and structural variations.

bioRxiv · Feb 24, 2023 · PreprintCancer Biology

APOBEC3A Catalyzes Mutation and Drives Carcinogenesis In Vivo

E. Law, R. Levin-Klein, M. Jarvis, H. Kim, P. Argyris, M. Carpenter, G. Starrett, L. Larson, M. Burns, R. Vogel, S. Stavrou, A. Aguilera, S. Wagner, D. Largaespada, T. Starr, , R. Harris

This study shows APOBEC3A promotes tumorigenesis in mice and supports its role in causing mutations in human cancers.

bioRxiv · Dec 27, 2019Cancer Biology

A rabbit monoclonal antibody against the antiviral and cancer genomic DNA mutating enzyme APOBEC3B

W. Brown, E. Law, M. Carpenter, P. Argyris, R. Levin-Klein, A. Ranum, A. Molan, C. Forster, B. Anderson, L. Lackey, R. Harris

This paper describes the generation and characterization of a rabbit monoclonal antibody against APOBEC3B, showing its potential as a research tool and clinical biomarker for cancer.

bioRxiv · Jan 7, 2019Cancer Biology