Author

R. O'Donnell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:imaging· 2 Organism:zebrafish· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

K. I. Baek· 2 shared T. Hsiai· 2 shared A. Bullock· 1 shared A. L. Marsden· 1 shared A. Lai· 1 shared A. Ramirez-Mata· 1 shared A. Tomilov· 1 shared C. J. Frost· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBioengineering

K. I. Baek

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Computational Simulations of the 4-D Micro-Circulatory Network in Zebrafish Tail Amputation and Regeneration

M. Roustaei, K. I. Baek, Z. Wang, S. Cavallero, S. Satta, A. Lai, R. O'Donnell, V. Vedula, Y. Ding, A. L. Marsden, T. Hsiai

This study uses computational fluid dynamics to model microvascular changes in zebrafish tail regeneration, showing dynamic shifts in wall shear stress and flow rate during vascular remodeling.

bioRxiv · Feb 10, 2021 · PreprintBioengineering

An embryonic zebrafish model to screen disruption of gut-vascular-barriers upon exposure to ambient ultrafine particles

K. I. Baek, Y. Qian, C.-C. Chang, R. O'donnell, E. Soleimanian, C. Sioutas, R. Li, T. Hsiai

This study uses zebrafish embryos to show that exposure to ultrafine particles disrupts the gut-vascular barrier by modulating Notch signaling.

bioRxiv · Oct 28, 2020Bioengineering

Novel mTORC1 inhibitors kill Glioblastoma stem cells

J. A. Sandoval, A. Tomilov, S. Datta, S. Allen, R. O'Donnell, J. Angelastro, G. Cortopassi

This paper identifies novel mTORC1 inhibitors that effectively kill GBM stem cells and shows their potential as adjuvant therapy when combined with temozolomide.

bioRxiv · Jun 17, 2020Pharmacology & Toxicology

β-Caryophyllene Enhances the Transcriptional Upregulation of Cholesterol Biosynthesis in Breast Cancer Cells

M. Y. Mboge, A. Ramirez-Mata, A. Bullock, R. O'Donnell, J. Mathias, J. Davila, C. J. Frost, S. C. Frost

This study shows that β-caryophyllene increases cholesterol and fatty acid synthesis in breast cancer cells, potentially as a response to its cytotoxic effects.

bioRxiv · Mar 6, 2019Cancer Biology