R. P. Rai

Western diet dampens T regulatory cell function to fuel hepatic inflammation in nonalcoholic fatty liver disease

This study shows that a western diet impairs T regulatory cell function in NAFLD, leading to chronic inflammation and fibrosis, and suggests restoring Treg function as a potential therapy.

Selective targeting of α4β7/MAdCAM-1 axis suppresses liver fibrosis by reducing proinflammatory T cell recruitment to the liver

This study shows that targeting the α4β7/MAdCAM-1 axis reduces proinflammatory T cell recruitment to the liver, thereby suppressing liver fibrosis progression in a mouse model.