SARS-CoV-2 S protein ACE2 interaction reveals novel allosteric targets
G. S. Anand, R. Palur, N. K. Tulsian, F. Samsudin, X. Qian, K. Purushotorman, G. Yue, M. K. McQueen, J. Lescar, P. Bond, P. A. McAry
The paper investigates how ACE2 binding to SARS-CoV-2 Spike protein allosterically affects proteolysis at distal cleavage sites and highlights potential therapeutic targets.
bioRxiv · Oct 13, 2020Biochemistry