Author

R. Prunskaite-Hyyryläinen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

L. Lehtiö· 2 shared Y. Ashok· 2 shared A. Galera-Prat· 1 shared B. E. Lippok· 1 shared B. Lüscher· 1 shared C. Vagaggini· 1 shared C. Vela-Rodriguez· 1 shared D. Mennerich· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

L. Lehtiö

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2 papers

Recent·Most cited

BiochemistrybioRxivJan 30, 2023

The E3 ubiquitin ligase DTX3L and the deubiquitinase USP28 fine-tune DNA double strand repair through mutual regulation of their protein levels

D. Mennerich, Y. Ashok, C. Vela-Rodriguez…·T. Kietzmann

This paper identifies a regulatory feedback loop between DTX3L and USP28 that modulates DNA double-strand break repair by controlling protein levels and repair pathway efficiency.

DOI 10.1016/j.isci.2025.112990

experimental assaywet-lab / biochemical assay

𝕏 PostBluesky

BiochemistrybioRxivAug 29, 2022

benzothiazole scaffold as versatile nicotinamide mimic allowing nanomolar inhibition of different PARP enzymes

S. Murthy, M. G. Nizi, M. M. Maksimainen…·L. Lehtiö

The paper identifies a benzothiazole scaffold that inhibits multiple PARP enzymes with nanomolar potency, showing selectivity for mono-ARTs and poly-ARTs.

DOI 10.1021/acs.jmedchem.2c01460

humanexperimental assay

𝕏 PostBluesky