Author

R. S. Chapkin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Wilson· 1 shared E. Malmberg· 1 shared G. Heravi· 1 shared I. Levental· 1 shared I. Podgorski· 1 shared J. L. Symons· 1 shared J. Li· 1 shared K. R. Levental· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Wilson

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Targeting Fatty Acid Desaturase I Inhibits Renal Cancer Growth Via ATF3-mediated ER Stress Response

G. Heravi, Z. Liu, M. Herroon, A. Wilson, Y. Y. Fan, Y. Jiang, N. Vakeesan, L. Tao, Z. Peng, K. Zhang, J. Li, R. S. Chapkin, I. Podgorski, W. Liu

This study shows that inhibiting FADS1 reduces renal cancer growth by inducing ER stress and ATF3-mediated responses, highlighting FADS1 as a therapeutic target.

bioRxiv · Mar 23, 2024 · PreprintCancer Biology

Lipidomic and biophysical homeostasis of mammalian membranes counters dietary lipids perturbations to maintain cellular fitness

K. R. Levental, E. Malmberg, J. L. Symons, Y.-Y. Fan, R. S. Chapkin, R. Ernst, I. Levental

The paper shows that mammalian cells counteract dietary lipid perturbations through lipidomic remodeling to maintain membrane physical properties and cellular fitness.

bioRxiv · Feb 11, 2020Cell Biology