Author

R. S. Hamilton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Bioengineering· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Assay:proteomics· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:development & morphogenesis· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 3

Frequent Co-Authors

X. X. Zhao· 3 shared A. Appios· 2 shared A. Moffett· 2 shared A. Sharkey· 2 shared N. McGovern· 2 shared A. C. Ferguson-Smith· 1 shared A. Carnicer-Lombarte· 1 shared A. L. Rutz· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersImmunology

X. X. Zhao

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Post-translational regulation of the Numb/Notch pathway in neurogenesis and cancer by Dlk2

S. B. Telerman, R. S. Hamilton, B. Shaw, J. D. Dimitrov, B. Steventon, A. C. Ferguson-Smith

This study identifies Dlk2 as a regulator of Numb/Notch pathway in zebrafish neurogenesis and human cancer, showing its role in modulating Numb phosphorylation and Notch signaling.

bioRxiv · Jul 20, 2023 · PreprintCell Biology

Maternal group 2 innate lymphoid cells control fetal growth and protect from endotoxin-induced abortion in mice

E. Balmas, B. M. Rana, R. S. Hamilton, N. Shreeve, J. Kieckbusch, I. Aye, D. A. Hawkes, S. Trotter, J. Lopez-Trello, H. E. Yong, S. Valenti, A. N. Sferruzzi-Perri, F. Gaccioli, A. N. McKenzie, F. Colucci

This study shows that maternal group 2 innate lymphoid cells (ILC2s) support fetal growth and prevent endotoxin-induced abortion in mice by modulating immune responses and placental function.

bioRxiv · Feb 15, 2023 · PreprintImmunology

Foreign body reaction is triggered in vivo by cellular mechanosensing of implants stiffer than host tissue

A. Carnicer-Lombarte, D. G. Barone, I. B. Dimov, R. S. Hamilton, M. Prater, X. X. Zhao, A. L. Rutz, G. G. Malliaras, S. P. Lacour, C. E. Bryant, J. W. Fawcett, K. Franze

The paper shows that implants stiffer than host tissue trigger a foreign body reaction via mechanosensing, and soft coatings reduce inflammation and fibrosis.

bioRxiv · Dec 28, 2022 · PreprintBioengineering

Human HLFneg placental erythro-myeloid progenitors give rise to HLA Class IIneg Hofbauer cells

J. R. Thomas, A. Appios, E. F. Calderbank, X. X. Zhao, R. S. Hamilton, A. Moffett, A. Sharkey, E. Laurenti, N. McGovern

The paper identifies placental erythro-myeloid progenitors (PEMPs) that generate Hofbauer cells, showing human primitive haematopoiesis occurs in the placenta, not just the yolk sac.

bioRxiv · Feb 26, 2022 · PreprintImmunology

Phenotypic and functional characterisation of first trimester human placental macrophages, Hofbauer cells.

J. Thomas, A. Appios, X. X. Zhao, R. A. Dutkiewicz, M. J. Donde, C. Lee, P. M. Naidu, C. Lee, J. Cerveira, B. Liu, F. Ginhoux, G. Burton, R. S. Hamilton, A. Moffett, A. Sharkey, N. McGovern

The paper characterizes first trimester human placental macrophages, identifying Hofbauer cells as HLA-DR-FOLR2+ macrophages with microbicidal properties and secreted factors influencing placental angiogenesis.

bioRxiv · Sep 3, 2020Immunology

Unbiased placental secretome characterization identifies candidates for pregnancy complications

T. Napso, X. Zhao, M. Ibanez Lligona, I. X. Sandovici, R. G. Kay, F. Gribble, F. Reimann, C. Meek, R. S. Hamilton, A. Sferruzzi-Perri

This study identifies placental hormones associated with pregnancy complications by analyzing the secretome of mouse placental cells and linking findings to human pregnancy outcomes.

bioRxiv · Jul 12, 2020Physiology