Author

R. S. Illingworth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Coates· 1 shared A. H. Y. Chan· 1 shared A. V. Kriegsheim· 1 shared C. J. Schofield· 1 shared E. E. Patton· 1 shared F. Rambow· 1 shared G. R. Grimes· 1 shared H. K. Mjoseng· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Coates

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

ALDH1A3-acetaldehyde metabolism potentiates transcriptionalheterogeneity in melanoma

Y. Lu, J. Travnickova, M. Badonyi, F. Rambow, A. Coates, Z. Khan, J. Marques, L. Murphy, P. Garcia-Martinez, R. Marais, P. Louphrasitthiphol, A. H. Y. Chan, C. J. Schofield, A. V. Kriegsheim, J. A. Marsh, , E. E. Patton

This study shows ALDH1A3 and ACSS2 coordinate acetaldehyde-acetyl-CoA metabolism with histone acetylation in melanoma, contributing to transcriptional heterogeneity and drug resistance.

bioRxiv · Oct 28, 2023Cancer Biology

DNA methylation directs polycomb-dependent 3D genome re- organisation in naive pluripotency

K. A. McLaughlin, I. M. Flyamer, J. P. Thomson, H. K. Mjoseng, R. Shukla, I. Williamson, G. R. Grimes, R. S. Illingworth, I. R. Adams, S. Pennings, R. R. Meehan, W. A. Bickmore

This study shows that DNA hypomethylation in 2i conditions alters polycomb-mediated 3D genome organization in ESCs, but functional characteristics of 2i cells remain unchanged.

bioRxiv · Jan 22, 2019Cell Biology