Author

I. M. Flyamer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Assay:Hi-C· 1 Organism:human· 1

Frequent Co-Authors

B. J. H. Dequeker· 1 shared G. R. Grimes· 1 shared H. B. Brandao· 1 shared H. K. Mjoseng· 1 shared I. F. Davidson· 1 shared I. Gaspar· 1 shared I. R. Adams· 1 shared I. Williamson· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

B. J. H. Dequeker

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Author profile →

2 papers

Recent·Most cited

MCM complexes are barriers that restrict cohesin-mediated loop extrusion

B. J. H. Dequeker, H. B. Brandao, M. J. Scherr, J. Gassler, S. Powell, I. Gaspar, I. M. Flyamer, W. Tang, R. Stocsits, I. F. Davidson, J.-M. Peters, K. E. Duderstadt, L. A. Mirny, K. Tachibana

The paper shows MCM complexes block cohesin-mediated loop extrusion, reducing CTCF-anchored loops and TAD boundary insulation in G1 phase.

bioRxiv · Oct 15, 2020Cell Biology

DNA methylation directs polycomb-dependent 3D genome re- organisation in naive pluripotency

K. A. McLaughlin, I. M. Flyamer, J. P. Thomson, H. K. Mjoseng, R. Shukla, I. Williamson, G. R. Grimes, R. S. Illingworth, I. R. Adams, S. Pennings, R. R. Meehan, W. A. Bickmore

This study shows that DNA hypomethylation in 2i conditions alters polycomb-mediated 3D genome organization in ESCs, but functional characteristics of 2i cells remain unchanged.

bioRxiv · Jan 22, 2019Cell Biology