Author

R. Sivakumar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 2 Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Research Focus:benchmarking· 1 Research Focus:dimensionality reduction· 1 Research Focus:imputation· 1

Frequent Co-Authors

C. R. Stoltzfus· 2 shared M. Y. Gerner· 2 shared A. K. Glaser· 1 shared A. K. Hempton· 1 shared A. Palojarvi· 1 shared A. Tripathi· 1 shared B. E. Olin Pope· 1 shared B. J. Beliveau· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

C. R. Stoltzfus

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Poly-basic peptides and polymers as new drug candidate against Plasmodium falciparum

R. Sivakumar, K. Floyd, E. Jessey, J. Kim Kim, P. Bayguinov, J. A. J. Fitzpatrick, D. Goldfarb, M. Jovanovic, A. Tripathi, S. Djuranovic, S. Pavlovic Djuranovic

This study shows poly-lysine peptides and their modifications can reduce Plasmodium falciparum in human erythrocytes in vitro, with potential as new antimalarial drugs.

bioRxiv · Sep 16, 2023 · PreprintMicrobiology

Highly scalable and standardized organ-on-chip platform with TEER for biological barrier modeling

H. T. H. Nguyen, S.-L. Rissanen, M. Peltokangas, T. Laakkonen, J. Kettunen, L. Barthod, R. Sivakumar, A. Palojarvi, P. Junttila, J. Talvitie, M. Bassis, S. L. Nickels, J. C. Schwamborn, S. Mosser, P. Singh

The paper introduces a scalable organ-on-chip platform for high-throughput in vitro assays, demonstrating its use in modeling biological barriers and drug testing.

bioRxiv · Aug 2, 2023Bioengineering

Multi-Parameter Quantitative Imaging of Tumor Microenvironments Reveals Perivascular Immune Niches Associated with Anti-Tumor Immunity

C. R. Stoltzfus, R. Sivakumar, L. Kunz, B. E. Olin Pope, E. Menietti, D. Speziale, R. Adelfio, M. Bacac, S. Colombetti, M. Perro, M. Y. Gerner

This study uses spatial analysis to show that perivascular immune niches are associated with anti-tumor immunity and are enhanced by immunotherapy.

bioRxiv · Jun 17, 2021Immunology

Genome-wide identification of genetic requirements of Pseudomonas aeruginosa PAO1 for rat cardiomyocyte (H9C2) infection by insertion sequencing

J. Ranjani, R. Sivakumar, P. Gunasekaran, J. Rajendhran

The paper uses insertion sequencing to identify genetic requirements of Pseudomonas aeruginosa PAO1 for infecting rat cardiomyocytes, finding key roles for flagella, T3SS, pili, proteases, and OMVs.

bioRxiv · Mar 3, 2021 · PreprintMicrobiology

A hybrid open-top light-sheet microscope for multi-scale imaging of cleared tissues

A. K. Glaser, K. W. Bishop, L. A. Barner, E. A. Susaki, S. I. Kubota, G. Gao, R. B. Serafin, P. Balaram, E. Turschak, P. R. Nicovich, H. Lai, L. A. G. Lucas, Y. Yi, E. K. Nichols, H. Huang, , J. T. C. Liu

The paper introduces a hybrid light-sheet microscope that enables versatile multi-scale imaging of cleared tissues with varying resolution, geometry, and compatibility requirements.

bioRxiv · May 6, 2020Bioengineering