A combination of two small molecule toxin inhibitors provides pancontinental preclinical efficacy against viper snakebite
L.-O. Albulescu, C. Xie, S. Ainsworth, J. Alsolaiss, E. Crittenden, C. A. Dawson, R. Softley, K. E. Bartlett, R. A. Harrison, J. Kool, N. R. Casewell
This study shows that a combination of two small molecule inhibitors effectively neutralizes viper venom in vitro and prevents lethality in vivo across multiple regions.
bioRxiv · May 13, 2020Pharmacology & Toxicology