R. T. Annamalai

This paper converts tetracycline into carbonized nanomaterials with improved antioxidant and osteogenic properties while reducing cytotoxicity and adverse effects.

This study shows that mechanical instability causes fibrosis and immune dysregulation, impairing bone healing in fractures.

This study uses magnetic nanocomplexes with an external magnetic field to shift macrophage phenotype from proinflammatory to prohealing, promoting bone regeneration by modulating inflammation.

This study shows that biomechanical strain on muscle constructs influences bone phenotype through myokine secretion, with HIIT promoting healthier bone development than endurance training.

This paper develops microgels that sustain the immunomodulatory phenotype of mesenchymal stromal cells (MSC) by sequestering and releasing IFNγ, enhancing their therapeutic potential in inflammatory conditions.

This paper develops injectable microgels that promote bone regeneration and vascularization in critical-sized defects by combining osteogenic and vasculogenic properties.

This paper develops bioresponsive microspheres that release anti-inflammatory cytokines on-demand in osteoarthritic joints, reducing inflammation and preserving cartilage.

This study develops injectable osteogenic microtissues with MSCs to repair bone defects, showing that pre-differentiated MSCs promote complete bone bridging.