S. D. Robinson

Adaptive trade-offs between vertebrate defense and insect predation drive ant venom evolution

This study examines venom composition in 15 Neotropical ant species, finding trade-offs between venom functions for deterring vertebrates and paralyzing insects.

Evaluation of phantom doping materials in quantitative susceptibility mapping

This study evaluates four phantom doping materials for quantitative susceptibility mapping (QSM) by measuring molar susceptibility and test-retest repeatability at 3T and 7T.

Together, Neuropilin 1 and Neuropilin 2 direct α5 integrin trafficking through GTPase-activating-protein p120RasGAP in endothelial cells to promote fibronectin fibrillogenesis

This study identifies NRP1 and NRP2's role in regulating α5 integrin trafficking via p120RasGAP in endothelial cells, promoting fibronectin fibrillogenesis.

Deep-Learning-Enabled Differentiation between Intraprostatic Gold Fiducial Markers and Calcification in Quantitative Susceptibility Mapping

This paper develops a deep learning model using QSM to differentiate gold fiducial markers from calcification in prostate cancer patients, achieving higher accuracy than conventional MRI methods.

Endothelial neuropilin-1 and neuropilin-2 are essential for tumour angiogenesis

This study shows that targeting both endothelial neuropilin-1 and neuropilin-2 inhibits tumour angiogenesis and metastasis in mouse models.

Reciprocal interactions between the gut microbiome and mammary tissue mast cells promote metastatic dissemination of HR+ breast tumors

This study shows that an inflammatory gut microbiome promotes early metastasis of HR+ breast tumors by increasing mast cell activity in mammary tissue.

Endothelial NRP2 influences angiogenesis by regulating actin pattern development and α5-integrin-p-FAK complex recruitment to assembling adhesion sites

This study shows that endothelial NRP2 promotes angiogenesis by regulating actin dynamics and α5-integrin-p-FAK complex recruitment to adhesion sites, and its loss impairs tumor growth and retinal vascular development.

Convergent Evolution of Pain-Inducing Defensive Venom Components in Spitting Cobras

This study shows that three spitting cobra lineages independently evolved venom with increased pain-enhancing toxins, likely in response to hominin emergence.

Antibiotic-induced disturbances of the gut microbiota result in accelerated breast tumour growth via a mast cell-dependent pathway

This study shows antibiotic-induced gut microbiota disturbances accelerate breast tumour growth in mice via mast cell-dependent mechanisms.

NRP2 as an emerging angiogenic player; promoting endothelial cell adhesion and migration by regulating recycling of α5 integrin.

This study shows NRP2 promotes endothelial cell adhesion and migration by regulating α5 integrin recycling, distinct from NRP1's mechanism.

ADAMTS-1 and Syndecan-4 intersect in the regulation of cell migration and angiogenesis

This study shows ADAMTS-1 and syndecan-4 regulate cell migration and angiogenesis through MMP-9 and fibulin-1 interactions.

Perturbation of the gut microbiota by antibiotics results in accelerated breast tumour growth and metabolic dysregulation

This study shows that antibiotics disrupt the gut microbiota, leading to faster breast tumour growth and metabolic changes in mice.

The β3-integrin endothelial adhesome regulates microtubule dependent cell migration

This study shows that β3-integrin regulates microtubule stability in endothelial cells through Rcc2/Anxa2 and Rac1, affecting cell migration and angiogenesis.