SARS-CoV-2 accessory proteins ORF3a and ORF7a modulate autophagic flux and Ca2+ homeostasis in yeast
J. L. Garrido-Huarte, J. Fita-Torro, R. Viana, A. Pascual-Ahuir, M. Proft
This study shows SARS-CoV-2 ORF3a and ORF7a proteins affect autophagic flux and Ca2+ homeostasis in yeast by modulating autophagosome formation and processing from distinct cellular locations.
bioRxiv · Dec 29, 2022Microbiology