Conserved Roles of C. elegans and Human MANFs in Sulfatide Binding and Cytoprotection
M. Bai, R. Vozdek, A. Hnizda, C. Jiang, B. Wang, L. Kuchar, T. Li, Y. Zhang, C. Wood, L. Feng, Y. Dang, D. K. Ma
This study identifies C. elegans MANF orthologue, shows it binds sulfatide, and demonstrates sulfatide-dependent cytoprotection in both worms and mammalian cells.
bioRxiv · Feb 11, 2018Cell Biology